Medical Biotechnology
Medical biotechnology is defined as the application of biotechnological tools and techniques in which use of living cells, tissue, organs or bodies to research and produce diagnostic and pharmaceutical products that can be used for the diagnosis , prevention and treatment of diseases.
21th century is the fast growing time of medical biotechnology. Many national and international companies, research institute , government bodies are taking interest in research and development in medical biotechnology.
Medical biotechnology plays critical roles during emerging of new chronic diseases either microbials or non-microbials.One of the best example of Ebola disease and their causing agent is Ebola virus. The first drug of Ebola disease is ZmappTm which is developed by Mapp pharmaceuticals corporation and Bioleaf corporation. Both are international biotech companies.
Medical biotechnology is related our health, development of new drugs , work against bacterial, fungal , viral, cancer diseases and so on.
Contents of Medical Biotechnology:
Basic technologies
Molecular Cloning
DNA amplification and sequencing
Genomics
RNA interference
Gene therapy
Phage therapy
Concepts of immunology
Immune system and immune response
Cell mediated and humoral immunity
Immunological techniques
Stem cell therapy and bioengineered tissues
Antibiotics and vaccines
Human diseases
Causes and reason
Infectious and non-infectious
Genetic and autoimmune
Transmission of diseases
Diagnosis
Genetic basis of diseases
Chromosomal disorders
Gene mapping
Single gene and polygenic disorders
Mitochondrial disorders
Gene clustering
Immune Pathogenesis
Models of immune system defects
Inflammation and immune hypersensitivity disorders
Immunodeficiency and autoimmune disorders
Immunotherapy
Microbial Pathogenesis
Bacterial Infections
Bacterial genetics
Microbial biotransformation
Viral Infections
Antiviral drugs
Drug-resistance
Modulating Gene Expression
Recombinant DNA technology
Manipulation of gene expression in prokaryotes
Heterologous protein production in eukaryotic cells
Directed and random mutagenesis
Translational and transcriptional regulations
DNA shuffling
Cell and tissue engineering
Animal cell culture
Biomaterials
Stem cell technology
iPSCs and ESCs
Genetic engineering of plants
Molecular pharming and edible vaccines
Molecular diagnostics
Immunological approaches to detect protein biomarkers of disease
DNA-based approaches to disease diagnosis
Detecting RNA signatures of diseases
Fluorescence in situ hybridization
Genetic fingerprinting
Protein Therapeutics
Pharmaceuticals
Engineered bacteriophages
Recombinant antibodies
Enzymes
IL-10 modulations
Nucleic acid therapeutic agents and human gene therapy
Targeting specific mRNAs and DNAs
Viral and non-viral delivery systems
Prodrug activation therapy
Severe combined immunodeficiency
Vaccines
Advantages and limitations
Peptide vaccines
Dendritic cell vaccines
DNA vaccines
Attenuated and subunit vaccines
Adjuvants
Systems biology and evaluation of vaccines