by | May 28, 2021

An Emerging Endemic: Monkeypox

Writer- Deb Duhita Mondal (M. Tech Biotechnology, Heritage Institute of Technology, Kolkata)    The Monkeypox virus, a genetically unique DNA virus than the other viruses such as variola, vaccinia, ectromelia, camelpox, and cowpox viruses of the same Poxviridae...

Quality Sleep leads to Strong Immunity

Writer: Unnati Singhania (MSc. Biotechnology, Symbiosis School of Biological Sciences, Pune) Quality sleep is the measurement of how well you are sleeping and lack of sleep is more relevant in the current pandemic where people work from home, which eventually creates...

Can E-cigarettes also cause Cancer?

Image by Lindsay Fox from Pixabay Writer- Swastika Jha (MSc. Biotechnology, Symbiosis School of Biological Sciences, Pune) E-cigarettes were designed to be used as an alternative to smoking conventional cigarettes. It is a machine designed to deliver nicotine without...

WHAT IF? Water of Life is converted to the Water of Death!

Image Credit:  Original Images from Gerd Altmann & PDPics, Pixabay  A Case study written by   – Sachin Kumar (M.Sc. Student, Shoolini University) The river Ganga water is considered as holy water in the world since time immemorial, but what if you know that the...

A Journey Of Healthy Gut Bacteria Into Diseased Ones By The Use of Artificial Sweeteners

                                  Credit: Image by OpenClipart-Vectors from Pixabay  Writer-  Sachin Kumar,  M.Sc Biotechnology Research,  Shoolini University Nowadays, artificial sweeteners are widely used in the food industries on a very large scale, and it is...

Can Natural Killer (NK) Cells be used in fighting COVID ?

Writer: Swastika Jha (Banasthali Vidyapith, Jaipur, Rajasthan)

SARS- CoV-2 emerged rapidly inflicting contamination to hundreds of thousands and 1.5 million deaths in its first 12 months of the attack. Since then,it hasn’t recovered completely. A hyperactivated immune system is a concept to make contributions to combating this disorder with a contribution from NK Cells.


NK cells were early responders to SARS-CoV-2 contamination. Gene module for chemotaxis is brought on in lung with NK cells and lungs of sufferers with COVID-19 incorporate an excessive degree of chemokines. This chemokine manufacturing indicates that CXCR3 and CCR5 are crucial for homing NK cells to the lungs in acute SARS-CoV-2 contamination.


NK cells show an activated response in acute SARS-CoV-2 contamination. In excessive coronavirus disorder 2019 (COVID-19), adaptive-like NK cells are discovered at better frequencies in circulation.

From the currently available studies, the extent of NK molecular activationor proliferation isn’t related strongly to COVID-19 severity. Future studies are to be done to find whether or not the growth of NK cells is required to unleash the total antiviral potential of NK cells in opposition to SARS-CoV-2 contamination or whether or not those cells are as a substitute contributing to COVID-19 pathogenesis.

NK cells have an immediate and direct killing effect on SARS-CoV-2 infected cells, as well as these cells also participate in antibody-dependent cellular cytotoxicity. 

A current synthetic intelligencetechnique recognized an ‘excessive viral pandemic middle gene signature’ that highlighted NK molecular senescence as crucial determinants for excessive or deadly COVID-19. It became lately recommended that IL-15 are often connected to NK molecular disorder in COVID-19.

It’s evident from recent studies that these cells can have a vigorous response to viral infections. A hyperactivated immune system is thought to contribute to severe Covid19 with contribution from NK cells. Hence further studies are made to confirm the role of NK CELLS in defeating coronavirus.


Björkström, N.K., Strunz, B. & Ljunggren, HG. Natural killer cells in antiviral immunity. Nat Rev Immunol (2021).